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Early T-cell precursor leukemia: a subtype of high risk childhood acute lymphoblastic leukemia
null
《医学前沿(英文)》 2012年 第6卷 第4期 页码 416-420 doi: 10.1007/s11684-012-0224-4
Acute lymphoblastic leukemia includes T-cell acute lymphoblastic leukemia (T-ALL) and B-cell acute lymphoblastic leukemia (B-ALL). In children, T-ALL usually has a worse prognosis than B-ALL, although childhood T-ALL prognoses have improved remarkably. The varying outcomes among T-ALL cases suggest that an unrecognized biological heterogeneity may contribute to chemo-resistance. Deep exploration of T-lymphocyte development in recent years has found a subgroup of patients with a phenotype that resembles early T-cell precursor, which confers a much poorer prognosis than any other form of T-ALL. This novel subtype of T-ALL was called early T-cell precursor acute lymphoblastic leukemia (ETP-ALL). Flow cytometry data from T-ALL patients enrolled in Shanghai Children’s Medical Center between July 2002 and October 2010 were assessed according to Dr. Campana’s protocol. Among total 89 T-ALL cases, 74 cases had enough immunophenotype data available to differentiate between ETP (CD1a-, CD8-, CD5dim, at least one marker of stem cell or myeloid lineage) and non-ETP. From these 74 subjects, 12 ETP-ALL cases (16.2%) were identified. The event-free survival (EFS) rate at 66.8 months was 11.1%±10.1% for ETP-ALL and 57.6%±5.6% for non-ETP-ALL (P=0.003). The overall survival rates were 13.3%±11.0% for ETP-ALL and 64.7%±6.3% for non-ETP-ALL (P=0.002). Our findings demonstrate that early T-cell precursor leukemia is a very high-risk subtype of acute lymphoblastic leukemia with poor prognosis.
关键词: acute lymphoblastic leukemia early T precursor prognosis
Jiangbo Jin, Yun Zhu, Jicheng Jang, Shuxiao Wang, Jia Xing, Pen-Chi Chiang, Shaojia Fan, Shicheng Long
《环境科学与工程前沿(英文)》 2021年 第15卷 第2期 doi: 10.1007/s11783-020-1323-0
关键词: Response surface model Hill-climbing algorithm Ozone pollution Precursor emissions Control strategy
Ripen NSENGA MD, Longxian CHENG PhD, Mei’an HE PhD, Tangchun WU PhD,
《医学前沿(英文)》 2009年 第3卷 第4期 页码 437-442 doi: 10.1007/s11684-009-0074-x
关键词: natriuretic peptide precursor A coronary heart disease gene polymorphism allelic discrimination polymorphism single nucleotide
Carbon-coated lithium titanate: effect of carbon precursor addition processes on the electrochemical
Shilei Ding, Zelong Jiang, Jing Gu, Hongliang Zhang, Jiajia Cai, Dongdong Wang
《化学科学与工程前沿(英文)》 2021年 第15卷 第1期 页码 148-155 doi: 10.1007/s11705-020-2022-x
关键词: lithium titanate carbon-coated carbon precursor synthetic process
Correlation between carbon emissions and energy structure –Reliability analysis of low carbon target
Ben HUA
《能源前沿(英文)》 2011年 第5卷 第2期 页码 214-220 doi: 10.1007/s11708-010-0133-7
关键词: correlation carbon emissions energy consumption high carbon emissions energy mix target of emission reduction reliability
W. Widiyastuti, Adhi Setiawan, Sugeng Winardi, Tantular Nurtono, Heru Setyawan
《化学科学与工程前沿(英文)》 2014年 第8卷 第1期 页码 104-113 doi: 10.1007/s11705-014-1406-1
关键词: droplet hydroxyapatite particle CFD tubular furnace spray pyrolysis
Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia
Jianfeng Li, Yuting Dai, Liang Wu, Ming Zhang, Wen Ouyang, Jinyan Huang, Saijuan Chen
《医学前沿(英文)》 2021年 第15卷 第3期 页码 347-371 doi: 10.1007/s11684-020-0821-6
关键词: BCP-ALL subtypes translocation aneuploidy sequence mutations
Reducing CO emissions from the rebalancing operation of the bike-sharing system in Beijing
《工程管理前沿(英文)》 2023年 第10卷 第2期 页码 262-284 doi: 10.1007/s42524-021-0168-y
关键词: bike-sharing CO2 emissions environmental benefit partitioning strategy rebalancing problem
Greenhouse gas emissions mitigation and economic viability of sugar crops in China
《农业科学与工程前沿(英文)》 doi: 10.15302/J-FASE-2023529
● Sugarcane and sugar beet yield and carbon footprint rose with time but profit declined
关键词: Economic profits GHG emissions labor input nitrogen input sugar
Decomposition analysis applied to energy and emissions: A literature review
《工程管理前沿(英文)》 页码 625-639 doi: 10.1007/s42524-023-0270-4
关键词: index decomposition analysis structural decomposition analysis production decomposition analysis energy CO2 emissions
Impacts of inter-sectoral trade on carbon emissions—a case of China in 2007
Xiuqi FANG, Benyong WEI, Yuan WANG
《环境科学与工程前沿(英文)》 2012年 第6卷 第3期 页码 387-402 doi: 10.1007/s11783-012-0396-9
关键词: international trade carbon emissions input-output analysis China
Hydrothermal synthesis of crystalline α-/β-MnO2 nanorods via γ-MnOOH nanorod precursors
ZHANG Weixin, REN Xiangbin, YANG Zeheng, WANG Hua, WANG Qiang, HUANG Fei
《化学科学与工程前沿(英文)》 2007年 第1卷 第4期 页码 365-371 doi: 10.1007/s11705-007-0066-9
关键词: obtained -MnOOH precursor Besides high-resolution transmission precursor
Field scale measurement of greenhouse gas emissions from land applied swine manure
Devin L. Maurer, Jacek A. Koziel, Kelsey Bruning
《环境科学与工程前沿(英文)》 2017年 第11卷 第3期 doi: 10.1007/s11783-017-0915-9
关键词: Climate change Emissions Greenhouse gases Land application Swine manure
Abating transport GHG emissions by hydrogen fuel cell vehicles: Chances for the developing world
Han HAO, Zhexuan MU, Zongwei LIU, Fuquan ZHAO
《能源前沿(英文)》 2018年 第12卷 第3期 页码 466-480 doi: 10.1007/s11708-018-0561-3
Fuel cell vehicles, as the most promising clean vehicle technology for the future, represent the major chances for the developing world to avoid high-carbon lock-in in the transportation sector. In this paper, by taking China as an example, the unique advantages for China to deploy fuel cell vehicles are reviewed. Subsequently, this paper analyzes the greenhouse gas (GHG) emissions from 19 fuel cell vehicle utilization pathways by using the life cycle assessment approach. The results show that with the current grid mix in China, hydrogen from water electrolysis has the highest GHG emissions, at 3.10 kgCO2/km, while by-product hydrogen from the chlor-alkali industry has the lowest level, at 0.08 kgCO2/km. Regarding hydrogen storage and transportation, a combination of gas-hydrogen road transportation and single compression in the refueling station has the lowest GHG emissions. Regarding vehicle operation, GHG emissions from indirect methanol fuel cell are proved to be lower than those from direct hydrogen fuel cells. It is recommended that although fuel cell vehicles are promising for the developing world in reducing GHG emissions, the vehicle technology and hydrogen production issues should be well addressed to ensure the life-cycle low-carbon performance.
关键词: hydrogen fuel cell vehicle life cycle assessment energy consumption greenhouse gas (GHG) emissions China
Daoroong SUNGTHONG, Debra R. REINHART
《环境科学与工程前沿(英文)》 2011年 第5卷 第2期 页码 149-158 doi: 10.1007/s11783-011-0324-4
关键词: hydrogen sulfide emissions construction and demolition waste autotrophic denitrification landfill biocovers
标题 作者 时间 类型 操作
Early T-cell precursor leukemia: a subtype of high risk childhood acute lymphoblastic leukemia
null
期刊论文
Enhancement of the polynomial functions response surface model for real-time analyzing ozone sensitivity
Jiangbo Jin, Yun Zhu, Jicheng Jang, Shuxiao Wang, Jia Xing, Pen-Chi Chiang, Shaojia Fan, Shicheng Long
期刊论文
The role of natriuretic peptide precursor A gene polymorphism in the development of coronary heart disease
Ripen NSENGA MD, Longxian CHENG PhD, Mei’an HE PhD, Tangchun WU PhD,
期刊论文
Carbon-coated lithium titanate: effect of carbon precursor addition processes on the electrochemical
Shilei Ding, Zelong Jiang, Jing Gu, Hongliang Zhang, Jiajia Cai, Dongdong Wang
期刊论文
Correlation between carbon emissions and energy structure –Reliability analysis of low carbon target
Ben HUA
期刊论文
Particle formation of hydroxyapatite precursor containing two components in a spray pyrolysis process
W. Widiyastuti, Adhi Setiawan, Sugeng Winardi, Tantular Nurtono, Heru Setyawan
期刊论文
Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia
Jianfeng Li, Yuting Dai, Liang Wu, Ming Zhang, Wen Ouyang, Jinyan Huang, Saijuan Chen
期刊论文
Impacts of inter-sectoral trade on carbon emissions—a case of China in 2007
Xiuqi FANG, Benyong WEI, Yuan WANG
期刊论文
Hydrothermal synthesis of crystalline α-/β-MnO2 nanorods via γ-MnOOH nanorod precursors
ZHANG Weixin, REN Xiangbin, YANG Zeheng, WANG Hua, WANG Qiang, HUANG Fei
期刊论文
Field scale measurement of greenhouse gas emissions from land applied swine manure
Devin L. Maurer, Jacek A. Koziel, Kelsey Bruning
期刊论文
Abating transport GHG emissions by hydrogen fuel cell vehicles: Chances for the developing world
Han HAO, Zhexuan MU, Zongwei LIU, Fuquan ZHAO
期刊论文